function

FuncNet is a distributed protein function comparison pipeline, funded by the European Union's EMBRACE Network of Excellence.

The objective of FuncNet is to provide an open platform for the computational prediction and analysis of protein function.

It is designed to answer questions like:

Given one set of proteins which are known to share a particular biological function...

... which of these other proteins also share that function?

This service allows you to submit requests to the FuncNet pipeline, which are then forwarded on to the component prediction services.

For a guide to using FuncNet, including source code and example SOAP messages, please see http://funcnet.eu/getting-started/

The individual prediction services within FuncNet are also available for direct querying; for details, please see http://funcnet.eu/wsdls/

CODA predicts functional relationships between dissimilar proteins which have domains found in one protein in another species.

This version of CODA uses Pfam domains (http://pfam.sanger.ac.uk/).

It has one operation: ScorePairwiseRelations

CODA is a component of the FuncNet function prediction pipeline. For more information, including sample requests, see http://funcnet.eu/

CODA predicts functional relationships between dissimilar proteins which have domains found in one protein in another species.

This version of CODA uses CATH domains (http://cathdb.info).

It has one operation: ScorePairwiseRelations

This takes two lists of proteins (UniProt primary accession IDs) and returns pairs which are predicted to be functionally related.

CODA is a component of the FuncNet function prediction pipeline. For more information, including sample requests, see http://funcnet.eu/

hiPPI predicts the function of proteins based on protein-protein interaction data inherited from better-studied proteins with homologous domains.

It has one operation: ScorePairwiseRelations

This takes two lists of proteins (UniProt primary accession IDs) and returns pairs which are predicted to be functionally related.

hiPPI is a component of the FuncNet function prediction pipeline. For more information, including sample requests, see http://funcnet.eu/

GECO predicts the function of proteins based on correlated patterns of gene expression in microarray experiments.

It has one operation: ScorePairwiseRelations

This takes two lists of proteins (UniProt primary accession IDs) and returns pairs which are predicted to be functionally related.

GECO is a component of the FuncNet function prediction pipeline. For more information, including sample requests, see http://funcnet.eu/