MHC class I pathway

NetChop 3.1 server produces neural network predictions for cleavage sites of the human proteasome. The method is described in detail in the following article:

Current version: (3.1)
The role of the proteasome in generating cytotoxic T cell epitopes:Insights obtained from improved predictions of proteasomal cleavage.
M Nielsen, C Lundegaard, O Lund, and C Kesmir.
Immunogenetics., 57(1-2):33-41, 2005.

Original version:
Prediction of proteasome cleavage motifs by neural networks.
C. Kesmir, A. Nussbaum, Hansjorg Schild, Vincent Detours, and S. Brunak, Prot. Eng., 15(4): 287-296, 2002.