structure

Given the amino acid sequence of a putative alpha-helical membrane protein, TOPCONS predicts the topology of the protein, i.e. a specification of the membrane spanning segments and their IN/OUT orientation relative to the membrane. The prediction is a consensus from five different topology prediction algorithms: SCAMPI (single sequence mode), SCAMPI (multiple sequence mode), PRODIV-TMHMM, PRO-TMHMM and OCTOPUS.

This service allows the CATH database to be searched by protein structure.

NB This service is not currently active. It is still in development -- check back here for updates. The WSDL posted may change between now and the first release.