Hidden Markov Model

SignalP - Prediction of signal peptide and cleavage sites in gram+, gram- and eukaryotic amino acid sequences

PASSED

This Web Service implements SignalP v. 3.1. It predicts the presence and
location of signal peptide cleavage sites in amino acid sequences from
different organisms: Gram-positive prokaryotes, Gram-negative prokaryotes,
and eukaryotes. The method incorporates a prediction of cleavage sites
and a signal peptide/non-signal peptide prediction based on a combination
of several artificial neural networks and hidden Markov models. The method
is described in detail in the following article:

Improved prediction of signal peptides: SignalP 3.0.

TMHMM - Prediction of transmembrane helices in proteins

As yet this is untested.

TMHMM is a method for prediction transmembrane helices based on a hidden Markov model and
developed by Anders Krogh and Erik Sonnhammer. The method is described in detail in the
following articles:

Predicting transmembrane protein topology with a hidden Markov model: Application
to complete genomes. A. Krogh, B. Larsson, G. von Heijne, and E. L. L. Sonnhammer.
J. Mol. Biol., 305(3):567-580, January 2001.
PDF: http://www.binf.ku.dk/krogh/publications/pdf/KroghEtal01.pdf

A hidden Markov model for predicting transmembrane helices in protein sequences.

SHRIMP

WARNING

SHRIMP

CATH/Gene3D HMMScan (draft WSDL)

As yet this is untested.

This service allows the CATH and Gene3D HMM libraries to be searched with a given amino acid sequence (or any one of various database identifiers representing a sequence).

NB This service is not currently active. It is still in development -- check back here for updates. The WSDL posted may change between now and the first release.

RNAmmer

PASSED

The RNAmmer 1.2 server predicts 5s/8s, 16s/18s, and 23s/28s ribosomal RNA in full genome sequences. This page is the entry of the CBS Prediction Server for RNAmmer. RNAmmer is available also as a Web Service described by the following WSDL file. Please read the instructions on the RNAmmer Web Services section.
This pages allows academic users to download RNAmmer